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This article is an orphan, as few or no other articles link to it. Please introduce links to this page from related articles; suggestions are available. (December 2009) In genetics, underdominance is the opposite of overdominance. It is the selection against the mean of a population distribution, causing disruptive selection and divergent genotypes. Underdominance can also be described as homozygote advantage, wherein homozygous individuals have a higher fitness than heterozygous individuals. See also Natural selection Heterozygote advantage This genetics article is a stub. You can help Wikipedia by expanding it. v • d • e